(WAND) – As medical cannabis continues to evolve, a study based in Israel found that CBD reduces symptoms of ADHD and autism in children. The national organization for the reform of marijuana laws advocates for the legalization of marijuana for medical and non-medical use in the U.S.

“Patients in the autistic community in Israel have been using cannabis as a medicine for quite some time. it is considered safe and effective as a treatment for patients,” said Paul Armentano, deputy director of NORML.

According to Armentano, the research is based on an observational study in Israel. Across a three-to-six-month timespan, 109 children and young adults with autism or ADHD were evaluated. Of the sample, 53 participants were assessed by their schoolteachers using the Conners’ Teacher Rating Scale before CBD cannabis treatment and after treatment.

The U.S. FDA has not approved cannabis to be used to treat any disease or condition. However, the agency has approved one cannabis derived drug called Epidiolex. This is different than THC or CBD marijuana.

“THC is the primary mood-altering component in cannabis. It also possesses a number of therapeutic properties. It is an appetite stimulant. It’s an anti-nausea and it’s analgesic. CBD is another component in the cannabis plant. Unlike THC, it is not a euphoric-inducing component,” Armentano said.

NORML said research like that in Israel shows cannabis is safe and effective compared to commonly prescribed medications like opioids.